Hypersensitivity angiitis

M13_HYPERANG

hypersensitivity vasculitis: Disorder characterized by a vasculitic syndrome associated with exposure to an antigen such as a drug, infectious agent, or other foreign or endogenous substance. Its pathophysiology includes immune complex deposition and a wide range of skin lesions. Hypersensitivity or allergy is present in some but not all cases.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 M31.0
Hospital discharge: ICD-9 4462A
Hospital discharge: ICD-8 4461
Cause of death: ICD-10 M31.0
Cause of death: ICD-9 4462A
Cause of death: ICD-8 4461

130

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

117

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Check minimum number of events None

117

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Include endpoints None

117

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M13_HYPERANG

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M31
Name in latin Angi(i)tis hypersensitivitatis

Summary Statistics

Key figures

All Female Male
Number of individuals 115 59 56
Unadjusted prevalence (%) 0.04 0.03 0.04
Mean age at first event (years) 54.11 54.05 54.16

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: M13_HYPERANG – Hypersensitivity angiitis
GWS hits: 1

Survival analyses between endpoints

Plot

before Hypersensitivity angiitis
after Hypersensitivity angiitis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hypersensitivity angiitis