Fibromyalgia

M13_FIBROMYALGIA

fibromyalgia: A chronic disorder of unknown etiology characterized by pain, stiffness, and tenderness in the muscles of neck, shoulders, back, hips, arms, and legs. Other signs and symptoms include headaches, fatigue, sleep disturbances, and painful menstruation.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 M79.7
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 M79.7
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

1647

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1647

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Check minimum number of events None

1647

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Include endpoints None

1647

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M13_FIBROMYALGIA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M79

Summary Statistics

Key figures

All Female Male
Number of individuals 1595 1491 104
Unadjusted prevalence (%) 0.52 0.86 0.08
Mean age at first event (years) 52.41 52.42 52.31

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.12 9.86 [4.84, 20.08] 2.8e-10 21
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: M13_FIBROMYALGIA – Fibromyalgia
GWS hits: 1

Survival analyses between endpoints

Plot

before Fibromyalgia
after Fibromyalgia

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