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Palmar fascial fibromatosis [Dupuytren]

DOIDEFOMESHSNOMED PheWeb

M13_DUPUTRYEN

Plantar Fibromatosis: A superficial fibromatosis arising from soft tissue of the plantar regions. It is characterized by the presence of spindle-shaped fibroblasts, hypercellularity, and an infiltrative growth pattern.

Endpoint definition

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FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 M72.0
Hospital discharge: ICD-9 7286
Hospital discharge: ICD-8 7339
Cause of death: ICD-10 M72.0
Cause of death: ICD-9 7286
Cause of death: ICD-8 7339

4226

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

4158

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Check minimum number of events None

4158

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Include endpoints None

4158

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M13_DUPUTRYEN

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M72
Name in latin Fibromatosis aponeurosis palmaris

Summary Statistics

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Key figures

All Female Male
Number of individuals 4051 1076 2975
Unadjusted prevalence (%) 1.31 0.62 2.20
Mean age at first event (years) 55.10 50.28 56.84

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.95 [0.69, 1.31] 7.6e-1 691
15 years 0.00 0.80 [0.62, 1.05] 1.0e-1 369
5 years 0.00 1.15 [0.90, 1.47] 2.7e-1 132
1 year 0.00 1.28 [0.84, 1.95] 2.4e-1 27

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_DUPUTRYEN – Palmar fascial fibromatosis [Dupuytren]
GWS hits: 20

Survival analyses between endpoints

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Plot

before Palmar fascial fibromatosis [Dupuytren]
after Palmar fascial fibromatosis [Dupuytren]

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Palmar fascial fibromatosis [Dupuytren]

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