Radial styloid tenosynovitis [de Quervain]

M13_DEQUERVAIN

De Quervain disease: Stenosing tenosynovitis of the abductor pollicis longus and extensor pollicis brevis tendons in the first dorsal wrist compartment. The presenting symptoms are usually pain and tenderness at the radial styloid. The cause is almost always related to overuse injury or is associated with rheumatoid arthritis.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 M65.4

Hospital discharge: ICD-9 7270A

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 M65.4

Cause of death: ICD-9 7270A

Cause of death: ICD-8 $!$

1157

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1157

Check minimum number of events None

1157

Include endpoints None

1157

M13_DEQUERVAIN

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 M65

Name in latin Tenosynovitis regionis processus styloidis radii (de Quervain)

Similar endpoints

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List of similar endpoints to Radial styloid tenosynovitis [de Quervain] based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1121	916	205
Unadjusted prevalence (%)	0.36	0.53	0.15
Mean age at first event (years)	46.44	46.16	47.69

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.75 [0.89, 3.45]	1.1e-1	25
15 years	0.01	1.42 [0.66, 3.05]	3.6e-1	15
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_DEQUERVAIN – Radial styloid tenosynovitis [de Quervain]
GWS hits: 0

Survival analyses between endpoints

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Plot

before Radial styloid tenosynovitis [de Quervain]
after Radial styloid tenosynovitis [de Quervain]

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Table

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Drugs most likely to be purchased after Radial styloid tenosynovitis [de Quervain]

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