Cervicocranial syndrome

M13_CERVICOCRANSDR

Barre-Lieou syndrome: A syndrome that involves occipital head aches, nystagmus on head movement, tinnitus, spasms, blurred vision, corneal hyperaesthesia, and corneal ulcers.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 M53.0

Hospital discharge: ICD-9 7232

Hospital discharge: ICD-8 7281

Cause of death: ICD-10 M53.0

Cause of death: ICD-9 7232

Cause of death: ICD-8 7281

2360

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2349

Check minimum number of events None

2349

Include endpoints None

2349

M13_CERVICOCRANSDR

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 M53

Name in latin Syndroma cervicocraniale

Similar endpoints

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List of similar endpoints to Cervicocranial syndrome based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	2281	1611	670
Unadjusted prevalence (%)	0.74	0.93	0.50
Mean age at first event (years)	52.66	51.98	54.30

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.28 [1.59, 3.26]	7.1e-6	139
15 years	0.01	1.52 [1.09, 2.11]	1.2e-2	69
5 years	0.00	2.06 [1.34, 3.18]	9.6e-4	30
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_CERVICOCRANSDR – Cervicocranial syndrome
GWS hits: 0

Survival analyses between endpoints

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Plot

before Cervicocranial syndrome
after Cervicocranial syndrome

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Table

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Drugs most likely to be purchased after Cervicocranial syndrome

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