Other and unspecified vasculitis limited to skin

L12_VASCULITISNAS

hypersensitivity vasculitis: Disorder characterized by a vasculitic syndrome associated with exposure to an antigen such as a drug, infectious agent, or other foreign or endogenous substance. Its pathophysiology includes immune complex deposition and a wide range of skin lesions. Hypersensitivity or allergy is present in some but not all cases.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 L95.8, L95.9

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 L95.8, L95.9

Cause of death: ICD-9 $!$

Cause of death: ICD-8 $!$

457

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

457

Check minimum number of events None

457

Include endpoints None

457

L12_VASCULITISNAS

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other and unspecified vasculitis limited to skin based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	440	257	183
Unadjusted prevalence (%)	0.14	0.15	0.14
Mean age at first event (years)	57.68	57.62	57.76

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.13	10.64 [5.83, 19.41]	1.3e-14	64
15 years	0.02	3.71 [1.93, 7.11]	8.2e-5	21
5 years	0.01	7.40 [3.62, 15.11]	4.0e-8	23
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_VASCULITISNAS – Other and unspecified vasculitis limited to skin
GWS hits: 0

Survival analyses between endpoints

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Plot

before Other and unspecified vasculitis limited to skin
after Other and unspecified vasculitis limited to skin

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Table

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Drugs most likely to be purchased after Other and unspecified vasculitis limited to skin

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