Other and unspecified disorders of skin and subcutaneous tissue

L12_SKINSUBCUTISNAS

skin disease: Any deviation from the normal structure or function of the skin or subcutaneous tissue that is manifested by a characteristic set of symptoms and signs.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 L98.80, L98.88, L98.9

Hospital discharge: ICD-9 7019X|7098|7099

Hospital discharge: ICD-8 70198|7090[8-9]

Hospital discharge: excluded ICD-9 7098A|7098B

Cause of death: ICD-10 L98.80, L98.88, L98.9

Cause of death: ICD-9 7019X|7098|7099

Cause of death: ICD-8 70198|7090[8-9]

Cause of death: excluded ICD-9 7098A|7098B

1622

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1617

Check minimum number of events None

1617

Include endpoints None

1617

L12_SKINSUBCUTISNAS

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other and unspecified disorders of skin and subcutaneous tissue based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1574	993	581
Unadjusted prevalence (%)	0.51	0.57	0.43
Mean age at first event (years)	52.04	50.08	55.39

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.01	1.16 [0.56, 2.40]	7.0e-1	125
15 years	0.00	0.73 [0.40, 1.32]	3.0e-1	53
5 years	0.00	1.74 [1.02, 2.94]	4.1e-2	34
1 year	0.00	4.98 [2.74, 9.06]	1.5e-7	18

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_SKINSUBCUTISNAS – Other and unspecified disorders of skin and subcutaneous tissue
GWS hits: 0

Survival analyses between endpoints

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Plot

before Other and unspecified disorders of skin and subcutaneous tissue
after Other and unspecified disorders of skin and subcutaneous tissue

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Table

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Drugs most likely to be purchased after Other and unspecified disorders of skin and subcutaneous tissue

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