Pemphigoid

DOID EFO MESH SNOMED PheWeb

L12_PEMPHIGOID

bullous pemphigoid: Bullous pemphigoid (BP) is the most common form of autoimmune bullous dermatosis.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 L12

Cause of death: ICD-10 L12

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

Check minimum number of events None

Include endpoints

L12_PEMPHIGOID_BULL

L12_PEMPHIGOID_CICA

L12_BULLLOUS_CHILD

L12_EPIDERMOLYSIS_ACQ

L12_PEMPHIGOID_NAS

462

L12_PEMPHIGOID

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 L10-L14

Name in latin Pemphigoides

Similar endpoints

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List of similar endpoints to Pemphigoid based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	453	236	217
Unadjusted prevalence (%)	0.15	0.14	0.16
Mean age at first event (years)	67.79	66.18	69.55

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	3.45 [1.86, 6.39]	8.7e-5	83
15 years	0.01	0.84 [0.42, 1.67]	6.2e-1	18
5 years	0.00	3.22 [1.87, 5.56]	2.6e-5	36
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_PEMPHIGOID – Pemphigoid
GWS hits:

Survival analyses between endpoints

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Plot

before Pemphigoid
after Pemphigoid

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Table

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Drugs most likely to be purchased after Pemphigoid

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