Localized scleroderma [morphea]

L12_LOCALSCLERODERMA

localised scleroderma: Localized scleroderma is the skin localized form of scleroderma (see this term) characterized by fibrosis of the skin causing cutaneous plaques or strips.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 L94.0

Hospital discharge: ICD-9 7010A

Hospital discharge: ICD-8 70100

Cause of death: ICD-10 L94.0

Cause of death: ICD-9 7010A

Cause of death: ICD-8 70100

279

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

279

Check minimum number of events None

279

Include endpoints None

279

L12_LOCALSCLERODERMA

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 L94

Name in latin Scleroderma circumscriptum

Similar endpoints

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List of similar endpoints to Localized scleroderma [morphea] based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	265	216	49
Unadjusted prevalence (%)	0.09	0.12	0.04
Mean age at first event (years)	50.04	50.48	48.12

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_LOCALSCLERODERMA – Localized scleroderma [morphea]
GWS hits: 0

Survival analyses between endpoints

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Plot

before Localized scleroderma [morphea]
after Localized scleroderma [morphea]

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Table

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Drugs most likely to be purchased after Localized scleroderma [morphea]

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