Hypertrophic scar

L12_HYPETROPHICSCAR

osteoarthritis: A noninflammatory degenerative joint disease occurring chiefly in older persons, characterised by degeneration of the articular cartilage, hypertrophy of bone at the margins and changes in the synovial membrane. It is accompanied by pain and stiffness, particularly after prolonged activity.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 L91.0

Hospital discharge: ICD-9 7014B

Hospital discharge: ICD-8 70130

Cause of death: ICD-10 L91.0

Cause of death: ICD-9 7014B

Cause of death: ICD-8 70130

1183

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1183

Check minimum number of events None

1183

Include endpoints None

1183

L12_HYPETROPHICSCAR

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 L91

Name in latin Cicatrix cheloides

Similar endpoints

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List of similar endpoints to Hypertrophic scar based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1126	807	319
Unadjusted prevalence (%)	0.36	0.47	0.24
Mean age at first event (years)	40.38	38.73	44.54

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.01	0.97 [0.52, 1.79]	9.2e-1	42
15 years	0.00	0.67 [0.34, 1.34]	2.6e-1	19
5 years	0.00	1.92 [0.98, 3.75]	5.7e-2	12
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_HYPETROPHICSCAR – Hypertrophic scar
GWS hits: 4

Survival analyses between endpoints

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Plot

before Hypertrophic scar
after Hypertrophic scar

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Table

Loading survival analyses table

Drugs most likely to be purchased after Hypertrophic scar

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