Dermatitis herpetiformis


dermatitis herpetiformis: Dermatitis herpetiformis (DH) is a chronic autoimmune subepidermal bullous disease characterized by grouped pruritic lesions such as papules, urticarial plaques, erythema, and herpetiform vesiculae, with a predominantly symmetrical distribution on extensor surfaces of the elbows (90%), knees (30%), shoulders, buttocks, sacral region, and face of children and adults. Erosions, excoriations and hyperpigmentation usually follow. DH may also appear as a consequence of gluten intolerance.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 L13.0
Hospital discharge: ICD-9 6940A|6942
Hospital discharge: ICD-8 693
Cause of death: ICD-10 L13.0
Cause of death: ICD-9 6940A|6942
Cause of death: ICD-8 693


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9


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Check minimum number of events None


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Include endpoints None


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Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L13
Name in latin Dermatitis herpetiformis

Summary Statistics

Key figures

All Female Male
Number of individuals 401 231 170
Unadjusted prevalence (%) 0.13 0.13 0.13
Mean age at first event (years) 44.79 42.50 47.89


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.73 [0.20, 2.67] 6.4e-1 31
15 years 0.00 0.71 [0.23, 2.18] 5.5e-1 18
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: L12_DERMATHERP – Dermatitis herpetiformis
GWS hits: 8

Survival analyses between endpoints


before Dermatitis herpetiformis
after Dermatitis herpetiformis

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Drugs most likely to be purchased after Dermatitis herpetiformis