Chronic ulcer of skin, not elsewhere classified

L12_CHRONICULCEROFSKIN

chronic ulcer of skin: ['Chronic skin ulceration is a common complication of diabetes, peripheral vascular disease, and disorders that decrease mobility. Local ulcer care will be successful only if the underlying cause is correctly identified and steps are taken to reverse it.']

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 L98.4

Hospital discharge: ICD-9 707[8-9]

Hospital discharge: ICD-8 707

Hospital discharge: excluded ICD-8 70700

Cause of death: ICD-10 L98.4

Cause of death: ICD-9 707[8-9]

Cause of death: ICD-8 707

Cause of death: excluded ICD-8 70700

1472

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1360

Check minimum number of events None

1360

Include endpoints None

1360

L12_CHRONICULCEROFSKIN

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 L98

Name in latin Ulcus chronicum cutis non alibi classificatum

Similar endpoints

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List of similar endpoints to Chronic ulcer of skin, not elsewhere classified based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1327	616	711
Unadjusted prevalence (%)	0.43	0.35	0.53
Mean age at first event (years)	61.05	59.54	62.35

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.07	5.54 [3.04, 10.13]	2.5e-8	270
15 years	0.01	1.88 [1.06, 3.33]	3.1e-2	72
5 years	0.01	6.77 [4.64, 9.87]	3.1e-23	110
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_CHRONICULCEROFSKIN – Chronic ulcer of skin, not elsewhere classified
GWS hits: 0

Survival analyses between endpoints

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Plot

before Chronic ulcer of skin, not elsewhere classified
after Chronic ulcer of skin, not elsewhere classified

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Table

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Drugs most likely to be purchased after Chronic ulcer of skin, not elsewhere classified

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