Ulcerative colitis (strict) with PSC

K11_UC_STRICT_PSC

ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions

K11_CHOLANGI_STRICT
and K11_UC_STRICT

169

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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Include endpoints

169

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K11_UC_STRICT_PSC

Extra metadata

First used in FinnGen datafreeze DF4

Summary Statistics

Key figures

All Female Male
Number of individuals 167 77 90
Unadjusted prevalence (%) 0.05 0.04 0.07
Mean age at first event (years) 29.82 29.90 29.75

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: K11_UC_STRICT_PSC – Ulcerative colitis (strict) with PSC
GWS hits: 0

Survival analyses between endpoints

Plot

before Ulcerative colitis (strict) with PSC
after Ulcerative colitis (strict) with PSC

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Drugs most likely to be purchased after Ulcerative colitis (strict) with PSC