Other diseases of the digestive system

DOID EFO MESH PheWeb

K11_OTHDIG

dumping syndrome: Gastrointestinal symptoms resulting from an absent or nonfunctioning pylorus.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 K90-K93

Cause of death: ICD-10 K90-K93

11906

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

11906

Check minimum number of events None

11906

Include endpoints

K11_COELIAC

K11_MALABSORB

K11_POSTOPDIS

K11_GIBLEEDING

K11_OTHDISDIG

K11_DISDIGINOTH

12631

K11_OTHDIG

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other diseases of the digestive system based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	12237	5879	6358
Unadjusted prevalence (%)	3.97	3.39	4.71
Mean age at first event (years)	56.30	52.29	60.01

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	3.59 [2.99, 4.31]	2.6e-42	2401
15 years	0.01	1.32 [1.09, 1.60]	3.8e-3	718
5 years	0.00	3.75 [3.22, 4.37]	1.3e-63	781
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_OTHDIG – Other diseases of the digestive system
GWS hits: 7

Survival analyses between endpoints

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Plot

before Other diseases of the digestive system
after Other diseases of the digestive system

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Table

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Drugs most likely to be purchased after Other diseases of the digestive system

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