Paralytic ileus and intestinal obstruction

K11_ILEUS

intestinal pseudo-obstruction: A type of ILEUS, a functional not mechanical obstruction of the INTESTINES. This syndrome is caused by a large number of disorders involving the smooth muscles (MUSCLE, SMOOTH) or the NERVOUS SYSTEM.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 K56

Cause of death: ICD-10 K56

5700

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

5700

Check minimum number of events None

5700

Include endpoints

K11_PARALIL

K11_INTUSS

K11_VOLVU

K11_IMPACT

K11_ADHE

K11_OTHILEUS

6586

K11_ILEUS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 K55-K63

Name in latin Ileus paralyticus sive obstructio intestini sine hernia

Similar endpoints

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List of similar endpoints to Paralytic ileus and intestinal obstruction based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

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Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	6359	3180	3179
Unadjusted prevalence (%)	2.06	1.83	2.35
Mean age at first event (years)	58.54	56.00	61.08

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	3.58 [2.82, 4.54]	1.6e-25	1394
15 years	0.01	1.27 [1.00, 1.60]	4.5e-2	364
5 years	0.00	3.49 [2.83, 4.30]	8.0e-32	360
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_ILEUS – Paralytic ileus and intestinal obstruction
GWS hits: 1

Survival analyses between endpoints

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Plot

before Paralytic ileus and intestinal obstruction
after Paralytic ileus and intestinal obstruction

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Table

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Drugs most likely to be purchased after Paralytic ileus and intestinal obstruction

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