Paralytic ileus and intestinal obstruction

K11_ILEUS

intestinal pseudo-obstruction: A type of ILEUS, a functional not mechanical obstruction of the INTESTINES. This syndrome is caused by a large number of disorders involving the smooth muscles (MUSCLE, SMOOTH) or the NERVOUS SYSTEM.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 K56
Cause of death: ICD-10 K56

5700

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

5700

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Check minimum number of events None

5700

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K11_ILEUS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 K55-K63
Name in latin Ileus paralyticus sive obstructio intestini sine hernia

Similar endpoints

Summary Statistics

Key figures

All Female Male
Number of individuals 6359 3180 3179
Unadjusted prevalence (%) 2.06 1.83 2.35
Mean age at first event (years) 58.54 56.00 61.08

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.58 [2.82, 4.54] 1.6e-25 1394
15 years 0.01 1.27 [1.00, 1.60] 4.5e-2 364
5 years 0.00 3.49 [2.83, 4.30] 8.0e-32 360
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: K11_ILEUS – Paralytic ileus and intestinal obstruction
GWS hits: 1

Survival analyses between endpoints

Plot

before Paralytic ileus and intestinal obstruction
after Paralytic ileus and intestinal obstruction

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Drugs most likely to be purchased after Paralytic ileus and intestinal obstruction