Unspecified acute lower respiratory infection

J10_ACUTELOWERNAS

pneumonia: An acute, acute and chronic, or chronic inflammation focally or diffusely affecting the lung parenchyma, caused by an infection in one or both of the lungs (by bacteria, viruses, fungi, or mycoplasma.). Symptoms include cough, shortness of breath, fevers, chills, chest pain, headache, sweating, and weakness.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 J22

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 46699

Cause of death: ICD-10 J22

Cause of death: ICD-9 $!$

Cause of death: ICD-8 46699

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

3642

J10_ACUTELOWERNAS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 J20-J22

Name in latin Infectio respiratoria inferior acuta non specificata

Similar endpoints

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List of similar endpoints to Unspecified acute lower respiratory infection based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	3525	1410	2115
Unadjusted prevalence (%)	1.14	0.81	1.57
Mean age at first event (years)	37.51	39.99	35.87

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.06	4.62 [3.37, 6.35]	2.6e-21	426
15 years	0.01	1.48 [1.12, 1.96]	5.5e-3	103
5 years	0.01	4.76 [3.57, 6.36]	3.1e-26	148
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: J10_ACUTELOWERNAS – Unspecified acute lower respiratory infection
GWS hits: 1

Survival analyses between endpoints

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Plot

before Unspecified acute lower respiratory infection
after Unspecified acute lower respiratory infection

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Table

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Drugs most likely to be purchased after Unspecified acute lower respiratory infection

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