Other/unspecified disorders of vestibular function

H8_VESTIFUNCNAS

vestibular disease: Pathological processes of the vestibular labyrinth which contains part of the balancing apparatus. Patients with vestibular diseases show instability and are at risk of frequent falls. [database_cross_reference: MESH:D015837]

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 H81.8, H81.9

Hospital discharge: ICD-9 386[8-9]

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 H81.8, H81.9

Cause of death: ICD-9 386[8-9]

Cause of death: ICD-8 $!$

1058

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

668

Check minimum number of events None

668

Include endpoints None

668

H8_VESTIFUNCNAS

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other/unspecified disorders of vestibular function based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	637	385	252
Unadjusted prevalence (%)	0.21	0.22	0.19
Mean age at first event (years)	59.12	58.86	59.51

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.86 [1.11, 3.14]	1.9e-2	80
15 years	0.01	1.07 [0.60, 1.90]	8.2e-1	38
5 years	0.00	2.32 [1.37, 3.93]	1.7e-3	23
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H8_VESTIFUNCNAS – Other/unspecified disorders of vestibular function
GWS hits: 0

Survival analyses between endpoints

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Plot

before Other/unspecified disorders of vestibular function
after Other/unspecified disorders of vestibular function

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Table

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Drugs most likely to be purchased after Other/unspecified disorders of vestibular function

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