Conductive and sensorineural hearing loss

H8_CONSENHEARINGLOSS

sensorineural hearing loss: Hearing loss in which the root cause lies in the inner ear or sensory organ (cochlea and associated structures) or the vestibulocochlear nerve (cranial nerve VIII).

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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Include endpoints

27355

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H8_CONSENHEARINGLOSS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

Summary Statistics

Key figures

All Female Male
Number of individuals 26501 12807 13694
Unadjusted prevalence (%) 8.59 7.38 10.14
Mean age at first event (years) 62.86 60.89 64.70

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.38 [1.21, 1.56] 1.0e-6 3006
15 years 0.01 0.88 [0.78, 1.00] 4.3e-2 1511
5 years 0.00 1.72 [1.54, 1.92] 1.3e-22 1007
1 year 0.00 2.16 [1.83, 2.55] 8.2e-20 246

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H8_CONSENHEARINGLOSS – Conductive and sensorineural hearing loss
GWS hits: 11

Survival analyses between endpoints

Plot

before Conductive and sensorineural hearing loss
after Conductive and sensorineural hearing loss

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Conductive and sensorineural hearing loss