Keratitis

H7_KERATITIS

keratitis: Inflammation of the cornea. [ NCIT:P378 ]

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 H16, H17, H18, H19*
Cause of death: ICD-10 H16, H17, H18, H19*

8710

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

8710

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Check minimum number of events None

8710

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H7_KERATITIS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Keratitis based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 8645 4783 3862
Unadjusted prevalence (%) 2.80 2.76 2.86
Mean age at first event (years) 50.16 49.69 50.75

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.12 [1.49, 3.03] 3.1e-5 576
15 years 0.01 1.28 [0.96, 1.71] 8.7e-2 259
5 years 0.00 2.68 [2.07, 3.47] 5.9e-14 187
1 year 0.00 4.85 [3.52, 6.67] 4.2e-22 67

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_KERATITIS – Keratitis
GWS hits: 9

Survival analyses between endpoints

Plot

before Keratitis
after Keratitis

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