keratitis: Inflammation of the cornea. [ NCIT:P378 ]

Endpoint definition

FinnGen phenotype data

321302 individuals

diagram downward connector

Apply sex-specific rule None


diagram downward connector

Check conditions None


diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 H16, H17, H18, H19*
Cause of death: ICD-10 H16, H17, H18, H19*


diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10


diagram downward connector

Check minimum number of events None


diagram downward connector

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Keratitis based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 8645 4783 3862
Unadjusted prevalence (%) 2.80 2.76 2.86
Mean age at first event (years) 50.16 49.69 50.75


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.12 [1.49, 3.03] 3.1e-5 576
15 years 0.01 1.28 [0.96, 1.71] 8.7e-2 259
5 years 0.00 2.68 [2.07, 3.47] 5.9e-14 187
1 year 0.00 4.85 [3.52, 6.67] 4.2e-22 67

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: H7_KERATITIS – Keratitis
GWS hits: 9

Survival analyses between endpoints


before Keratitis
after Keratitis

loading spinner Loading survival analyses plot