Keratitis

H7_KERATITIS

keratitis: Inflammation of the cornea. [ NCIT:P378 ]

Endpoint definition

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FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 H16, H17, H18, H19*
Cause of death: ICD-10 H16, H17, H18, H19*

8710

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

8710

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Check minimum number of events None

8710

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H7_KERATITIS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Keratitis based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 8645 4783 3862
Unadjusted prevalence (%) 2.80 2.76 2.86
Mean age at first event (years) 50.16 49.69 50.75

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.12 [1.49, 3.03] 3.1e-5 576
15 years 0.01 1.28 [0.96, 1.71] 8.7e-2 259
5 years 0.00 2.68 [2.07, 3.47] 5.9e-14 187
1 year 0.00 4.85 [3.52, 6.67] 4.2e-22 67

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_KERATITIS – Keratitis
GWS hits: 9

Survival analyses between endpoints

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Plot

before Keratitis
after Keratitis

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