Degeneration of the brain due to alcohol

MESH PheWeb

G6_ALCODEGEN

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 G31.2

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 G31.2

Cause of death: ICD-9 $!$

Cause of death: ICD-8 $!$

481

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

481

Check minimum number of events None

481

Include endpoints None

481

G6_ALCODEGEN

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 G31

Name in latin Degeneratio systematis nervosi ex alcohol (aethylico)

Similar endpoints

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List of similar endpoints to Degeneration of the brain due to alcohol based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Degeneration of nervous system due to alcohol

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	463	76	387
Unadjusted prevalence (%)	0.15	0.04	0.29
Mean age at first event (years)	58.86	54.78	59.66

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.10	8.37 [4.58, 15.31]	5.2e-12	169
15 years	0.02	4.04 [2.40, 6.81]	1.5e-7	66
5 years	0.01	9.31 [6.22, 13.95]	2.7e-27	59
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_ALCODEGEN – Degeneration of the brain due to alcohol
GWS hits: 0

Survival analyses between endpoints

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Plot

before Degeneration of the brain due to alcohol
after Degeneration of the brain due to alcohol

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Table

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Drugs most likely to be purchased after Degeneration of the brain due to alcohol

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