Mental and behavioural disorders due to tobacco

F5_TOBAC

nicotine dependence: Physical and psychological dependence on nicotine.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 F17
Hospital discharge: ICD-9 3051
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 F17
Cause of death: ICD-9 3051
Cause of death: ICD-8 $!$

1726

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1697

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Check minimum number of events None

1697

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Include endpoints None

1697

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F5_TOBAC

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F10-F19
Name in latin Perturbationes mentis et modi se gerendi ex usu tabaci

Summary Statistics

Key figures

All Female Male
Number of individuals 1641 814 827
Unadjusted prevalence (%) 0.53 0.47 0.61
Mean age at first event (years) 54.78 51.50 58.01

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.16 13.98 [9.75, 20.03] 8.0e-47 213
15 years 0.03 5.26 [3.57, 7.75] 4.6e-17 76
5 years 0.01 12.72 [9.07, 17.85] 4.0e-49 90
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: F5_TOBAC – Mental and behavioural disorders due to tobacco
GWS hits: 1

Survival analyses between endpoints

Plot

before Mental and behavioural disorders due to tobacco
after Mental and behavioural disorders due to tobacco

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Mental and behavioural disorders due to tobacco