Post-traumatic stress disorder


post-traumatic stress disorder: An anxiety disorder precipitated by an experience of intense fear or horror while exposed to a traumatic (especially life-threatening) event. The disorder is characterized by intrusive recurring thoughts or images of the traumatic event; avoidance of anything associated with the event; a state of hyperarousal and diminished emotional responsiveness. These symptoms are present for at least one month and the disorder is usually long-term.

Endpoint definition

FinnGen phenotype data

321302 individuals

diagram downward connector

Apply sex-specific rule None


diagram downward connector

Check conditions None


diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 F43.1
Hospital discharge: ICD-9 3098X
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 F43.1
Cause of death: ICD-9 3098X
Cause of death: ICD-8 $!$


diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9


diagram downward connector

Check minimum number of events None


diagram downward connector

Include endpoints None


diagram downward connector

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F43
Name in latin Perturbatio stressualis posttraumatica

Summary Statistics

Key figures

All Female Male
Number of individuals 1639 1321 318
Unadjusted prevalence (%) 0.53 0.76 0.24
Mean age at first event (years) 35.77 34.80 39.82


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 4.00 [2.24, 7.17] 3.0e-6 35
15 years 0.02 2.85 [1.58, 5.14] 4.9e-4 20
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: F5_PTSD – Post-traumatic stress disorder
GWS hits: 0

Survival analyses between endpoints


before Post-traumatic stress disorder
after Post-traumatic stress disorder

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Post-traumatic stress disorder