Post-traumatic stress disorder

F5_PTSD

post-traumatic stress disorder: An anxiety disorder precipitated by an experience of intense fear or horror while exposed to a traumatic (especially life-threatening) event. The disorder is characterized by intrusive recurring thoughts or images of the traumatic event; avoidance of anything associated with the event; a state of hyperarousal and diminished emotional responsiveness. These symptoms are present for at least one month and the disorder is usually long-term.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 F43.1

Hospital discharge: ICD-9 3098X

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 F43.1

Cause of death: ICD-9 3098X

Cause of death: ICD-8 $!$

1768

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1768

Check minimum number of events None

1768

Include endpoints None

1768

F5_PTSD

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 F43

Name in latin Perturbatio stressualis posttraumatica

Similar endpoints

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List of similar endpoints to Post-traumatic stress disorder based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1639	1321	318
Unadjusted prevalence (%)	0.53	0.76	0.24
Mean age at first event (years)	35.77	34.80	39.82

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	4.00 [2.24, 7.17]	3.0e-6	35
15 years	0.02	2.85 [1.58, 5.14]	4.9e-4	20
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_PTSD – Post-traumatic stress disorder
GWS hits: 0

Survival analyses between endpoints

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Plot

before Post-traumatic stress disorder
after Post-traumatic stress disorder

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Table

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Drugs most likely to be purchased after Post-traumatic stress disorder

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