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Mental and behavioural disorders due to opioids

DOIDEFOMESHSNOMED PheWeb

F5_OPIOIDS

opioid dependence: Disorders related or resulting from abuse or mis-use of opioids.

Endpoint definition

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FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 F11
Hospital discharge: ICD-9 3040|3055
Hospital discharge: ICD-8 304[0-1]
Cause of death: ICD-10 F11
Cause of death: ICD-9 3040|3055
Cause of death: ICD-8 304[0-1]

1164

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

962

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Check minimum number of events None

962

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Include endpoints None

962

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F5_OPIOIDS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F10-F19
Name in latin Perturbationes mentis et modi se gerendi ex usu opioidum

Summary Statistics

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Key figures

All Female Male
Number of individuals 909 398 511
Unadjusted prevalence (%) 0.29 0.23 0.38
Mean age at first event (years) 35.09 35.23 34.98

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.15 12.79 [7.66, 21.35] 1.8e-22 59
15 years 0.04 6.24 [3.52, 11.04] 3.3e-10 24
5 years 0.01 9.67 [5.04, 18.56] 8.6e-12 17
1 year 0.01 31.99 [14.48, 70.63] 1.0e-17 12

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_OPIOIDS – Mental and behavioural disorders due to opioids
GWS hits: 1

Survival analyses between endpoints

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Plot

before Mental and behavioural disorders due to opioids
after Mental and behavioural disorders due to opioids

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Mental and behavioural disorders due to opioids

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