Unspecified dementia

F5_DEMNAS

obsolete_dementia: ['An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.']

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 F03

Hospital discharge: ICD-9 290|2941

Hospital discharge: ICD-8 2900|29019

Cause of death: ICD-10 F03

Cause of death: ICD-9 290|2941

Cause of death: ICD-8 2900|29019

2850

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2842

Check minimum number of events None

2842

Include endpoints None

2842

F5_DEMNAS

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF3

Parent code in ICD-10 F00-F03

Name in latin Dementia non specificata

Similar endpoints

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List of similar endpoints to Unspecified dementia based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	2729	1169	1560
Unadjusted prevalence (%)	0.88	0.67	1.16
Mean age at first event (years)	77.61	79.15	76.46

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.13	9.82 [8.49, 11.35]	<1e-100	1798
15 years	0.02	2.34 [2.03, 2.70]	2.8e-31	380
5 years	0.01	6.68 [5.87, 7.61]	<1e-100	747
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_DEMNAS – Unspecified dementia
GWS hits: 4

Survival analyses between endpoints

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Plot

before Unspecified dementia
after Unspecified dementia

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Unspecified dementia

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