Idiopathic thrombocytopenic purpura


autoimmune thrombocytopenic purpura: An autoimmune disorder in which the number of circulating platelets is reduced due to their antibody-mediated destruction. ITP is a diagnosis of exclusion and is heterogeneous in origin.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 D69.3
Hospital discharge: ICD-9 2873A
Hospital discharge: ICD-8 28710
Cause of death: ICD-10 D69.3
Cause of death: ICD-9 2873A
Cause of death: ICD-8 28710


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9


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Check minimum number of events None


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Include endpoints None


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Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D69
Name in latin Purpura idiopathica thrombocytopenica

Similar endpoints

List of similar endpoints to Idiopathic thrombocytopenic purpura based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:


Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 605 328 277
Unadjusted prevalence (%) 0.20 0.19 0.21
Mean age at first event (years) 48.07 43.42 53.58


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 3.10 [1.80, 5.36] 5.0e-5 80
15 years 0.01 1.24 [0.67, 2.30] 4.9e-1 27
5 years 0.00 2.51 [1.33, 4.72] 4.5e-3 18
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: D3_ITP – Idiopathic thrombocytopenic purpura
GWS hits: 0

Survival analyses between endpoints


before Idiopathic thrombocytopenic purpura
after Idiopathic thrombocytopenic purpura

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Drugs most likely to be purchased after Idiopathic thrombocytopenic purpura