Defects in the complement system

DOID MESH PheWeb

D3_COMPLEMENTDEF

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 D84.1

Hospital discharge: ICD-9 2798B

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 D84.1

Cause of death: ICD-9 2798B

Cause of death: ICD-8 $!$

140

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

140

Check minimum number of events None

140

Include endpoints None

140

D3_COMPLEMENTDEF

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 D84

Name in latin Deficientia systematis complementi

Similar endpoints

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List of similar endpoints to Defects in the complement system based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	132	98	34
Unadjusted prevalence (%)	0.04	0.06	0.03
Mean age at first event (years)	41.68	43.08	37.64

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: D3_COMPLEMENTDEF – Defects in the complement system
GWS hits: 0

Survival analyses between endpoints

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Plot

before Defects in the complement system
after Defects in the complement system

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Table

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Drugs most likely to be purchased after Defects in the complement system

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