Chronic Coagulation defects

D3_COAGDEF

blood coagulation disease: A condition in which there is a deviation from or interruption of the normal coagulation properties of the blood.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

KELA reimbursements: KELA codes 126

113

Check pre-conditions, main-only, mode, ICD version None

113

Check minimum number of events None

113

Include endpoints

D3_HEREDFVIIIDEF

D3_HEREDFIXDEF

D3_VONVILLEBRAND

D3_HEREDFXIDEF

D3_HEREDOTHCLOFACTORS

505

D3_COAGDEF

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Chronic Coagulation defects based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	487	366	121
Unadjusted prevalence (%)	0.16	0.21	0.09
Mean age at first event (years)	38.41	38.51	38.10

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.30 [0.34, 4.94]	7.0e-1	19
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: D3_COAGDEF – Chronic Coagulation defects
GWS hits: 6

Survival analyses between endpoints

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Plot

before Chronic Coagulation defects
after Chronic Coagulation defects

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Chronic Coagulation defects

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