Vertebral, anorectal, cardiavascular, thracheoesophagial, renal and limb anomaly

PheWeb

Q17_VACTREL

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 Q8726|Q76|Q675|Q42|Q43[5-9]|Q20|Q21|Q22|Q23|Q24|Q25|Q26[1-4]|Q39|Q6[0-4]|Q69[0-1]|Q70[014]|Q71

Hospital discharge: excluded ICD-10 Q20.6, Q21.4, Q25.0, Q25.42, Q39.4, Q39.50, Q39.58, Q39.6

Cause of death: ICD-10 Q8726|Q76|Q675|Q42|Q43[5-9]|Q20|Q21|Q22|Q23|Q24|Q25|Q26[1-4]|Q39|Q6[0-4]|Q69[0-1]|Q70[014]|Q71

4081

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

4081

Check minimum number of events None

4081

Include endpoints None

4081

Q17_VACTREL

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF6v3

Similar endpoints

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List of similar endpoints to Vertebral, anorectal, cardiavascular, thracheoesophagial, renal and limb anomaly based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	3890	2065	1825
Unadjusted prevalence (%)	1.26	1.19	1.35
Mean age at first event (years)	38.44	36.60	40.52

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.10 [1.13, 3.90]	1.9e-2	219
15 years	0.01	1.28 [0.70, 2.34]	4.3e-1	103
5 years	0.00	2.41 [1.50, 3.87]	2.7e-4	58
1 year	0.00	6.79 [4.05, 11.40]	4.2e-13	30

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: Q17_VACTREL – Vertebral, anorectal, cardiavascular, thracheoesophagial, renal and limb anomaly
GWS hits:

Survival analyses between endpoints

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Plot

before Vertebral, anorectal, cardiavascular, thracheoesophagial, renal and limb anomaly
after Vertebral, anorectal, cardiavascular, thracheoesophagial, renal and limb anomaly

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Table

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Drugs most likely to be purchased after Vertebral, anorectal, cardiavascular, thracheoesophagial, renal and limb anomaly

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