Macular cyst

MACULAR_CYST

age-related macular degeneration: Age-related loss of vision in the central portion of the retina (macula), secondary to retinal degeneration.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 H35.36#
Hospital discharge: ICD-9 3625C
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 H35.36#
Cause of death: ICD-9 3625C
Cause of death: ICD-8 $!$

310

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

310

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Check minimum number of events None

310

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Include endpoints None

310

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MACULAR_CYST

Extra metadata

Level in the ICD hierarchy 5
First used in FinnGen datafreeze DF4
Parent code in ICD-10 H35

Summary Statistics

Key figures

All Female Male
Number of individuals 297 158 139
Unadjusted prevalence (%) 0.10 0.09 0.10
Mean age at first event (years) 70.20 69.71 70.77

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.83 [0.21, 3.20] 7.8e-1 10
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: MACULAR_CYST – Macular cyst
GWS hits: 0

Survival analyses between endpoints

Plot

before Macular cyst
after Macular cyst

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