Soft tissue disorders

M13_SOFTTISSUE

musculoskeletal system disease: A disease involving the musculoskeletal system. [database_cross_reference: MONDO:DesignPattern]

Endpoint definition

FinnGen phenotype data

321302 individuals

diagram downward connector

Apply sex-specific rule None

321302

diagram downward connector

Check conditions None

321302

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 M60-M79
Cause of death: ICD-10 M60-M79

75283

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

75283

diagram downward connector

Check minimum number of events None

75283

diagram downward connector
M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Soft tissue disorders based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 77694 45830 31864
Unadjusted prevalence (%) 25.18 26.41 23.60
Mean age at first event (years) 50.85 49.35 53.00

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.27 [1.14, 1.42] 1.2e-5 5049
15 years 0.01 0.92 [0.83, 1.01] 8.4e-2 2477
5 years 0.00 1.57 [1.42, 1.73] 1.3e-19 1131
1 year 0.00 3.10 [2.69, 3.57] 6.1e-56 419

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: M13_SOFTTISSUE – Soft tissue disorders
GWS hits: 6

Survival analyses between endpoints

Plot

before Soft tissue disorders
after Soft tissue disorders

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Soft tissue disorders