Hypersensitivity angiitis

M13_HYPERANG

hypersensitivity vasculitis: Disorder characterized by a vasculitic syndrome associated with exposure to an antigen such as a drug, infectious agent, or other foreign or endogenous substance. Its pathophysiology includes immune complex deposition and a wide range of skin lesions. Hypersensitivity or allergy is present in some but not all cases.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 M31.0

Hospital discharge: ICD-9 4462A

Hospital discharge: ICD-8 4461

Cause of death: ICD-10 M31.0

Cause of death: ICD-9 4462A

Cause of death: ICD-8 4461

130

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

117

Check minimum number of events None

117

Include endpoints None

117

M13_HYPERANG

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 M31

Name in latin Angi(i)tis hypersensitivitatis

Similar endpoints

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List of similar endpoints to Hypersensitivity angiitis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	115	59	56
Unadjusted prevalence (%)	0.04	0.03	0.04
Mean age at first event (years)	54.11	54.05	54.16

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_HYPERANG – Hypersensitivity angiitis
GWS hits: 1

Survival analyses between endpoints

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Plot

before Hypersensitivity angiitis
after Hypersensitivity angiitis

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Table

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Drugs most likely to be purchased after Hypersensitivity angiitis

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