Discontinuity and dislocation of ear ossicles

H8_DISCON

Otitis media: Inflammation of the anatomical structures of the middle ear, which is most often caused by an infectious process. Symptoms include erythema and edema of the tympanic membrane, pain, and possibly fever.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 H74.2

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 H74.2

Cause of death: ICD-9 $!$

Cause of death: ICD-8 $!$

108

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

108

Check minimum number of events None

108

Include endpoints None

108

H8_DISCON

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 H74

Name in latin Discontinuitas ossiculorum auditoriorum

Similar endpoints

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List of similar endpoints to Discontinuity and dislocation of ear ossicles based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	101	59	42
Unadjusted prevalence (%)	0.03	0.03	0.03
Mean age at first event (years)	51.07	48.48	54.72

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H8_DISCON – Discontinuity and dislocation of ear ossicles
GWS hits: 0

Survival analyses between endpoints

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Plot

before Discontinuity and dislocation of ear ossicles
after Discontinuity and dislocation of ear ossicles

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Table

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Drugs most likely to be purchased after Discontinuity and dislocation of ear ossicles

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