Astigmatism

H7_ASTIGMATISM

obsolete_astigmatism: ['Unequal curvature of the refractive surfaces of the eye. Thus a point source of light cannot be brought to a point focus on the retina but is spread over a more or less diffuse area. This results from the radius of curvature in one plane being longer or shorter than the radius at right angles to it. (Dorland, 27th ed).']

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 H52.2
Hospital discharge: ICD-9 3672
Hospital discharge: ICD-8 37000
Cause of death: ICD-10 H52.2
Cause of death: ICD-9 3672
Cause of death: ICD-8 37000

1146

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1146

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Check minimum number of events None

1146

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Include endpoints None

1146

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H7_ASTIGMATISM

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H52
Name in latin Astigmatismus

Summary Statistics

Key figures

All Female Male
Number of individuals 1069 598 471
Unadjusted prevalence (%) 0.35 0.34 0.35
Mean age at first event (years) 40.75 37.75 44.56

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.63 [1.45, 4.77] 1.5e-3 43
15 years 0.01 1.84 [1.01, 3.38] 4.8e-2 27
5 years 0.00 1.69 [0.76, 3.78] 2.0e-1 11
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_ASTIGMATISM – Astigmatism
GWS hits: 0

Survival analyses between endpoints

Plot

before Astigmatism
after Astigmatism

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