Disorders of refraction and accommodation

H7_REFRAACCOMMODIS

obsolete_refractive error: ['Deviations from the average or standard indices of refraction of the eye through its dioptric or refractive apparatus.']

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 H52

Cause of death: ICD-10 H52

5343

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

5343

Check minimum number of events None

5343

Include endpoints

H7_HYPERMETRO

H7_MYOPIA

H7_ASTIGMATISM

H7_ANISOMETROPIA

H7_PRESBYOPIA

H7_ACCOMMODIS

H7_REFRADISNAS

5620

H7_REFRAACCOMMODIS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 H49-H52

Name in latin Perturbationes refractionis et accommodationis (oculi)

Similar endpoints

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List of similar endpoints to Disorders of refraction and accommodation based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	5370	3437	1933
Unadjusted prevalence (%)	1.74	1.98	1.43
Mean age at first event (years)	41.00	40.02	42.74

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.69 [1.22, 2.35]	1.6e-3	198
15 years	0.01	1.08 [0.75, 1.54]	6.9e-1	109
5 years	0.00	1.71 [1.19, 2.46]	3.6e-3	52
1 year	0.00	2.69 [1.55, 4.67]	4.4e-4	15

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_REFRAACCOMMODIS – Disorders of refraction and accommodation
GWS hits: 2

Survival analyses between endpoints

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Plot

before Disorders of refraction and accommodation
after Disorders of refraction and accommodation

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Table

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Drugs most likely to be purchased after Disorders of refraction and accommodation

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