Family history of certain disabilities and chronic diseases leading to disablement

MESH PheWeb

Z21_FAMILY_HISTORY_CERTA_DISABILITI_CHRONIC_DISEA_LEADI_DISABL

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 Z82

Cause of death: ICD-10 Z82

892

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

892

Check minimum number of events None

892

Include endpoints None

892

Z21_FAMILY_HISTORY_CERTA_DISABILITI_CHRONIC_DISEA_LEADI_DISABL

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF4

Parent code in ICD-10 Z[8-9]

Similar endpoints

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List of similar endpoints to Family history of certain disabilities and chronic diseases leading to disablement based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	861	642	219
Unadjusted prevalence (%)	0.28	0.37	0.16
Mean age at first event (years)	41.77	40.06	46.80

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	4.16 [1.71, 10.12]	1.6e-3	14
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: Z21_FAMILY_HISTORY_CERTA_DISABILITI_CHRONIC_DISEA_LEADI_DISABL – Family history of certain disabilities and chronic diseases leading to disablement
GWS hits: 3

Survival analyses between endpoints

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Plot

before Family history of certain disabilities and chronic diseases leading to disablement
after Family history of certain disabilities and chronic diseases leading to disablement

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Table

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Drugs most likely to be purchased after Family history of certain disabilities and chronic diseases leading to disablement

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