obsolete_tuberculosis: ['A chronic, recurrent infection caused by the bacterium Mycobacterium tuberculosis. Tuberculosis (TB) may affect almost any tissue or organ of the body with the lungs being the most common site of infection. The clinical stages of TB are primary or initial infection, latent or dormant infection, and recrudescent or adult-type TB. Ninety to 95% of primary TB infections may go unrecognized. Histopathologically, tissue lesions consist of granulomas which usually undergo central caseation necrosis. Local symptoms of TB vary according to the part affected; acute symptoms include hectic fever, sweats, and emaciation; serious complications include granulomatous erosion of pulmonary bronchi associated with hemoptysis. If untreated, progressive TB may be associated with a high degree of mortality. This infection is frequently observed in immunocompromised individuals with AIDS or a history of illicit IV drug use. --2004', 'Any of the infectious diseases of man and other animals caused by species of MYCOBACTERIUM.']

Endpoint definition

FinnGen phenotype data

321302 individuals

diagram downward connector

Apply sex-specific rule None


diagram downward connector

Check conditions None


diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 A15, A16, A19, B90.9
Hospital discharge: ICD-9 01[1-2]|018
Hospital discharge: ICD-8 01[1-2]|018
Cause of death: ICD-10 A15, A16, A19, B90.9
Cause of death: ICD-9 01[1-2]|018
Cause of death: ICD-8 01[1-2]|018


diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9


diagram downward connector

Check minimum number of events None


diagram downward connector

Include endpoints None


diagram downward connector

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Tuberculosis based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 1610 603 1007
Unadjusted prevalence (%) 0.52 0.35 0.75
Mean age at first event (years) 49.74 45.59 52.22


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.78 [1.03, 3.06] 3.8e-2 555
15 years 0.01 1.20 [0.78, 1.84] 4.0e-1 247
5 years 0.00 2.45 [1.80, 3.33] 1.2e-8 142
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: TUBERCULOSIS – Tuberculosis
GWS hits:

Survival analyses between endpoints


before Tuberculosis
after Tuberculosis

loading spinner Loading survival analyses plot