severe traumatic brain injury, does not include concussion

MESH PheWeb

TRAUMBRAIN_NONCONCUS

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 S06.2, S06.3, S06.4, S06.5, S06.6, S06.7

Hospital discharge: ICD-9 85[1-2]

Hospital discharge: ICD-8 85[1-2]

Cause of death: ICD-10 S06.2, S06.3, S06.4, S06.5, S06.6, S06.7

Cause of death: ICD-9 85[1-2]

Cause of death: ICD-8 85[1-2]

5096

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

5096

Check minimum number of events None

5096

Include endpoints None

5096

TRAUMBRAIN_NONCONCUS

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to severe traumatic brain injury, does not include concussion based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	4927	1683	3244
Unadjusted prevalence (%)	1.60	0.97	2.40
Mean age at first event (years)	57.73	56.28	58.49

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	3.99 [3.07, 5.17]	2.5e-25	1159
15 years	0.01	1.47 [1.14, 1.91]	3.3e-3	334
5 years	0.00	3.35 [2.69, 4.18]	4.5e-27	300
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: TRAUMBRAIN_NONCONCUS – severe traumatic brain injury, does not include concussion
GWS hits: 0

Survival analyses between endpoints

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Plot

before severe traumatic brain injury, does not include concussion
after severe traumatic brain injury, does not include concussion

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after severe traumatic brain injury, does not include concussion

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