Toxic liver disease with fibrosis and cirrhosis of liver, drug-induced

PheWeb

TOXIC_LIVER_DISEA_W_FIBROSIS_CIRRH_LIVER

No definition available.

Endpoint definition

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FinnGen phenotype data

individuals

Apply sex-specific rule None

Check conditions None

Filter registries

Hospital discharge: ATC codes for adverse effects of drugs ANY

Hospital Discharge: ICD-10 K71.7#

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10

Check minimum number of events None

Include endpoints None

TOXIC_LIVER_DISEA_W_FIBROSIS_CIRRH_LIVER

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF5

Similar endpoints

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List of similar endpoints to Toxic liver disease with fibrosis and cirrhosis of liver, drug-induced based on the number of shared cases.

Broader endpoints:

None

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

All

Female

Male

Number of individuals

Unadjusted prevalence (%)

Mean age at first event (years)

?

Follow-up

Amount of time to look for the endpoint since entering the study. This is either either 1, 5, 15 years or the full study time from 1998 to 2019.

Absolute risk

Estimates the probability of dying from the current endpoint. Check the Documentation page for Mortality: absolute risk to get more details.

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Measures how much the risk of dying increases (HR > 1) or decreases (HR < 1).

Number of individuals (N)

Number of individuals having the current endpoint and died during the follow-up time.
Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: TOXIC_LIVER_DISEA_W_FIBROSIS_CIRRH_LIVER – Toxic liver disease with fibrosis and cirrhosis of liver, drug-induced
GWS hits:

Survival analyses between endpoints

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Plot

before Toxic liver disease with fibrosis and cirrhosis of liver, drug-induced
after Toxic liver disease with fibrosis and cirrhosis of liver, drug-induced

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Table

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Drugs most likely to be purchased after Toxic liver disease with fibrosis and cirrhosis of liver, drug-induced

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