Fracture of lower leg, including ankle

MESH PheWeb

ST19_FRACT_LOWER_LEG_INCLU_ANKLE

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 S82

Cause of death: ICD-10 S82

15852

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

15852

Check minimum number of events None

15852

Include endpoints None

15852

ST19_FRACT_LOWER_LEG_INCLU_ANKLE

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF4

Parent code in ICD-10 S8

Name in latin Fractura genus/cruris

Similar endpoints

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List of similar endpoints to Fracture of lower leg, including ankle based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	15359	8816	6543
Unadjusted prevalence (%)	4.98	5.08	4.85
Mean age at first event (years)	50.41	51.46	49.00

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.14 [1.73, 2.64]	1.3e-12	1202
15 years	0.01	1.32 [1.06, 1.65]	1.3e-2	565
5 years	0.00	2.89 [2.41, 3.48]	6.5e-30	362
1 year	0.00	4.52 [3.55, 5.75]	1.7e-34	111

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: ST19_FRACT_LOWER_LEG_INCLU_ANKLE – Fracture of lower leg, including ankle
GWS hits: 4

Survival analyses between endpoints

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Plot

before Fracture of lower leg, including ankle
after Fracture of lower leg, including ankle

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Table

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Drugs most likely to be purchased after Fracture of lower leg, including ankle

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