Selective serotonin reuptake inhibitors

PheWeb

SSRI

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Medicine purchases: ATC N06AB

83893

Check pre-conditions, main-only, mode, ICD version None

62785

Check minimum number of events

Min. number of events 3

62785

Include endpoints None

62785

SSRI

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Selective serotonin reuptake inhibitors based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	60669	41102	19567
Unadjusted prevalence (%)	19.66	23.69	14.49
Mean age at first event (years)	42.99	41.44	46.26

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.15 [1.92, 2.40]	2.5e-41	4651
15 years	0.01	1.55 [1.40, 1.71]	2.4e-17	2274
5 years	0.00	2.88 [2.63, 3.16]	<1e-100	1286
1 year	0.00	2.62 [2.23, 3.08]	8.9e-32	239

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: SSRI – Selective serotonin reuptake inhibitors
GWS hits:

Survival analyses between endpoints

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Plot

before Selective serotonin reuptake inhibitors
after Selective serotonin reuptake inhibitors

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Table

Loading survival analyses table

Drugs most likely to be purchased after Selective serotonin reuptake inhibitors

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