Use of hypnotics and sedatives

PheWeb

RX_N05C

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Medicine purchases: ATC N05C

88058

Check pre-conditions, main-only, mode, ICD version None

54303

Check minimum number of events

Min. number of events 3

54303

Include endpoints None

54303

RX_N05C

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF5

Similar endpoints

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List of similar endpoints to Use of hypnotics and sedatives based on the number of shared cases.

Broader endpoints:

Any prescribed medicine buy

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	52509	31558	20951
Unadjusted prevalence (%)	17.02	18.19	15.52
Mean age at first event (years)	52.43	51.00	54.59

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.89 [1.71, 2.09]	2.8e-35	8020
15 years	0.01	1.38 [1.26, 1.51]	2.0e-12	4160
5 years	0.00	2.08 [1.92, 2.27]	5.3e-65	1868
1 year	0.00	2.16 [1.87, 2.50]	6.8e-25	378

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: RX_N05C – Use of hypnotics and sedatives
GWS hits:

Survival analyses between endpoints

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Plot

before Use of hypnotics and sedatives
after Use of hypnotics and sedatives

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Table

Loading survival analyses table

Drugs most likely to be purchased after Use of hypnotics and sedatives

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