Tumor necrosis factor alpha inhibitors

RX_L04AB

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Medicine purchases: ATC L04AB

3081

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Check pre-conditions, main-only, mode, ICD version None

2941

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Check minimum number of events

Min. number of events 3

2941

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RX_L04AB

Extra metadata

First used in FinnGen datafreeze DF4

Summary Statistics

Key figures

All Female Male
Number of individuals 2843 1773 1070
Unadjusted prevalence (%) 0.92 1.02 0.79
Mean age at first event (years) 46.58 46.35 46.97

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 3.01 [1.37, 6.61] 6.1e-3 32
15 years 0.01 1.60 [0.68, 3.74] 2.8e-1 17
5 years 0.00 2.67 [1.19, 6.00] 1.8e-2 10
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: RX_L04AB – Tumor necrosis factor alpha inhibitors
GWS hits:

Survival analyses between endpoints

Plot

before Tumor necrosis factor alpha inhibitors
after Tumor necrosis factor alpha inhibitors

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Drugs most likely to be purchased after Tumor necrosis factor alpha inhibitors