Methotrexate

PheWeb

RX_L01BA01

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Medicine purchases: ATC L01BA01

5385

Check pre-conditions, main-only, mode, ICD version None

4420

Check minimum number of events

Min. number of events 3

4420

Include endpoints None

4420

RX_L01BA01

Extra metadata

First used in FinnGen datafreeze DF4

Similar endpoints

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List of similar endpoints to Methotrexate based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	4313	3040	1273
Unadjusted prevalence (%)	1.40	1.75	0.94
Mean age at first event (years)	47.20	46.21	49.58

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.16 [1.62, 2.90]	2.3e-7	378
15 years	0.01	1.65 [1.26, 2.15]	2.7e-4	198
5 years	0.00	1.88 [1.41, 2.50]	1.7e-5	63
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: RX_L01BA01 – Methotrexate
GWS hits:

Survival analyses between endpoints

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Plot

before Methotrexate
after Methotrexate

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Methotrexate

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