Benzodiazepine use

RX_BZD

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Medicine purchases: ATC N05BA

68403

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Check pre-conditions, main-only, mode, ICD version None

36117

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Check minimum number of events

Min. number of events 3

36117

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Include endpoints None

36117

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RX_BZD

Extra metadata

First used in FinnGen datafreeze DF4

Summary Statistics

Key figures

All Female Male
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Number of individuals
34940 21159 13781
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Unadjusted prevalence (%)
11.32 12.19 10.21
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Mean age at first event (years)
47.27 46.04 49.16

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Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.72 [1.52, 1.96] 6.8e-17 4445
15 years 0.01 1.21 [1.08, 1.36] 7.5e-4 2080
5 years 0.00 2.09 [1.86, 2.35] 9.6e-35 1008
1 year 0.00 2.58 [2.17, 3.07] 1.3e-26 242

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: RX_BZD – Benzodiazepine use
GWS hits:

Survival analyses between endpoints

Plot

before Benzodiazepine use
after Benzodiazepine use

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Benzodiazepine use