Voice disturbances

R18_VOICE_DISTU

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 R49
Hospital discharge: ICD-9 7844
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 R49
Cause of death: ICD-9 7844
Cause of death: ICD-8 $!$

6445

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

6404

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Check minimum number of events None

6404

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Include endpoints None

6404

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R18_VOICE_DISTU

Extra metadata

Level in the ICD hierarchy 3
Special VOICERESO
First used in FinnGen datafreeze DF4
Parent code in ICD-10 R47-R49
Name in latin Perturbationes vocis

Summary Statistics

Key figures

All Female Male
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Number of individuals
6196 4333 1863
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Unadjusted prevalence (%)
2.01 2.50 1.38
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Mean age at first event (years)
54.40 52.18 59.56

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Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.20 [0.85, 1.69] 2.9e-1 317
15 years 0.00 0.69 [0.48, 0.99] 4.4e-2 142
5 years 0.00 1.68 [1.23, 2.30] 1.2e-3 100
1 year 0.00 4.14 [2.85, 6.02] 1.1e-13 46

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: R18_VOICE_DISTU – Voice disturbances
GWS hits: 0

Survival analyses between endpoints

Plot

before Voice disturbances
after Voice disturbances

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Voice disturbances