Symptoms and signs involving the circulatory and respiratory systems

MESH PheWeb

R18_SYMPTOMS_SIGNS_INVOLVI_CIRCULATO_RESPI_SYSTEMS

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 R00-R09

Cause of death: ICD-10 R00-R09

88068

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

88068

Check minimum number of events None

88068

Include endpoints

R18_ABNORMALITI_HEART_BEAT

R18_CARDIAC_MURMU_OTHER_CARDIAC_SOUNDS

R18_GANGRENE_NOT_ELSEW_CLASSIFIED

R18_ABNORMAL_BLOOD_P_READI_WO_DIAGNOSIS

R18_HAEMORRHAGE_RESPI_PASSA

R18_COUGH

R18_ABNORMALITI_BREAT

R18_PAIN_THROAT_CHEST

R18_OTHER_SYMPTOMS_SIGNS_INVOLVI_CIRCULATO_RESPI_SYSTEMS

88501

R18_SYMPTOMS_SIGNS_INVOLVI_CIRCULATO_RESPI_SYSTEMS

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF4

Parent code in ICD-10 R

Name in latin Symptomata et signa ad systema circulatorium et systema respiratorium pertinentia

Similar endpoints

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List of similar endpoints to Symptoms and signs involving the circulatory and respiratory systems based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	85428	46694	38734
Unadjusted prevalence (%)	27.69	26.91	28.69
Mean age at first event (years)	54.11	52.28	56.31

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.37 [2.17, 2.60]	6.1e-79	8570
15 years	0.01	1.44 [1.32, 1.57]	3.4e-17	3679
5 years	0.00	2.83 [2.62, 3.06]	<1e-100	2490
1 year	0.00	8.46 [7.60, 9.42]	<1e-100	1550

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: R18_SYMPTOMS_SIGNS_INVOLVI_CIRCULATO_RESPI_SYSTEMS – Symptoms and signs involving the circulatory and respiratory systems
GWS hits: 0

Survival analyses between endpoints

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Plot

before Symptoms and signs involving the circulatory and respiratory systems
after Symptoms and signs involving the circulatory and respiratory systems

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Table

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Drugs most likely to be purchased after Symptoms and signs involving the circulatory and respiratory systems

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