Malaise and fatigue

MESH PheWeb

R18_MALAI_FATIG

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 R53

Hospital discharge: ICD-9 7807

Hospital discharge: ICD-8 79010

Cause of death: ICD-10 R53

Cause of death: ICD-9 7807

Cause of death: ICD-8 79010

12963

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

12916

Check minimum number of events None

12916

Include endpoints None

12916

R18_MALAI_FATIG

Extra metadata

Level in the ICD hierarchy 3

Special FATIGUE

First used in FinnGen datafreeze DF4

Parent code in ICD-10 R50-R69

Name in latin Aegritudo et lassitudo

Similar endpoints

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List of similar endpoints to Malaise and fatigue based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	12454	6856	5598
Unadjusted prevalence (%)	4.04	3.95	4.15
Mean age at first event (years)	64.21	61.60	67.41

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.10	7.87 [6.76, 9.16]	<1e-100	3008
15 years	0.01	1.76 [1.52, 2.04]	5.4e-14	533
5 years	0.01	6.11 [5.38, 6.94]	<1e-100	1211
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: R18_MALAI_FATIG – Malaise and fatigue
GWS hits: 0

Survival analyses between endpoints

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Plot

before Malaise and fatigue
after Malaise and fatigue

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Table

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Drugs most likely to be purchased after Malaise and fatigue

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