Hyperhidrosis

R18_HYPERHIDROSIS

hypohidrosis: diminished sweating in response to appropriate stimuli. While hyperhidrosis is a socially troubling but benign condition, hypohidrosis can lead to hyperthermia, heat exhaustion, heat stroke and potentially death.[1] An extreme case of hypohydrosis in which there is a complete absence of sweating and the skin is dry is termedanhidrosis.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 R61

Cause of death: ICD-10 R61

643

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

643

Check minimum number of events None

643

Include endpoints None

643

R18_HYPERHIDROSIS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF4

Parent code in ICD-10 R[5-6]

Name in latin Hyperhidrosis

Similar endpoints

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List of similar endpoints to Hyperhidrosis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

All

Female

Male

Number of individuals

609

439

170

Unadjusted prevalence (%)

0.20

0.25

0.13

Mean age at first event (years)

43.58

43.06

44.92

?

Follow-up

Amount of time to look for the endpoint since entering the study. This is either either 1, 5, 15 years or the full study time from 1998 to 2019.

Absolute risk

Estimates the probability of dying from the current endpoint. Check the Documentation page for Mortality: absolute risk to get more details.

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Measures how much the risk of dying increases (HR > 1) or decreases (HR < 1).

Number of individuals (N)

Number of individuals having the current endpoint and died during the follow-up time.
Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	3.34 [1.66, 6.72]	7.1e-4	15
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: R18_HYPERHIDROSIS – Hyperhidrosis
GWS hits: 0

Survival analyses between endpoints

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Plot

before Hyperhidrosis
after Hyperhidrosis

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Hyperhidrosis

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