Hyperhidrosis

R18_HYPERHIDROSIS

hypohidrosis: diminished sweating in response to appropriate stimuli. While hyperhidrosis is a socially troubling but benign condition, hypohidrosis can lead to hyperthermia, heat exhaustion, heat stroke and potentially death.[1] An extreme case of hypohydrosis in which there is a complete absence of sweating and the skin is dry is termedanhidrosis.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 R61

Cause of death: ICD-10 R61

643

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

643

Check minimum number of events None

643

Include endpoints None

643

R18_HYPERHIDROSIS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF4

Parent code in ICD-10 R[5-6]

Name in latin Hyperhidrosis

Similar endpoints

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List of similar endpoints to Hyperhidrosis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	609	439	170
Unadjusted prevalence (%)	0.20	0.25	0.13
Mean age at first event (years)	43.58	43.06	44.92

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	3.34 [1.66, 6.72]	7.1e-4	15
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: R18_HYPERHIDROSIS – Hyperhidrosis
GWS hits: 0

Survival analyses between endpoints

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Plot

before Hyperhidrosis
after Hyperhidrosis

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Table

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Drugs most likely to be purchased after Hyperhidrosis

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