Headache

MESH PheWeb

R18_HEADACHE1

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 R51

Hospital discharge: ICD-9 7840

Hospital discharge: ICD-8 79199

Cause of death: ICD-10 R51

Cause of death: ICD-9 7840

Cause of death: ICD-8 79199

21358

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

21296

Check minimum number of events None

21296

Include endpoints None

21296

R18_HEADACHE1

Extra metadata

Level in the ICD hierarchy 3

Special HEADACHE

First used in FinnGen datafreeze DF4

Parent code in ICD-10 R50-R69

Name in latin Cephalalgia

Similar endpoints

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List of similar endpoints to Headache based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	20401	14137	6264
Unadjusted prevalence (%)	6.61	8.15	4.64
Mean age at first event (years)	44.52	43.29	47.29

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.96 [1.58, 2.45]	1.9e-9	1155
15 years	0.01	1.26 [1.04, 1.52]	1.6e-2	532
5 years	0.00	2.16 [1.82, 2.56]	2.6e-18	275
1 year	0.00	5.60 [4.49, 6.98]	1.1e-52	137

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: R18_HEADACHE1 – Headache
GWS hits: 2

Survival analyses between endpoints

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Plot

before Headache
after Headache

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Table

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Drugs most likely to be purchased after Headache

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