Abnormal weight loss

R18_ABNORMAL_WEIGHT_LOSS

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

diagram downward connector

Apply sex-specific rule None

321302

diagram downward connector

Check conditions None

321302

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 R63.4
Hospital discharge: ICD-9 7832
Hospital discharge: ICD-8 78840
Cause of death: ICD-10 R63.4
Cause of death: ICD-9 7832
Cause of death: ICD-8 78840

2073

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1631

diagram downward connector

Check minimum number of events None

1631

diagram downward connector

Include endpoints None

1631

diagram downward connector
R18_ABNORMAL_WEIGHT_LOSS

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF5

Summary Statistics

Key figures

All Female Male
?
Number of individuals
1574 854 720
?
Unadjusted prevalence (%)
0.51 0.49 0.53
?
Mean age at first event (years)
56.53 52.93 60.79

?
Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 4.40 [2.38, 8.15] 2.4e-6 227
15 years 0.01 1.59 [0.85, 3.00] 1.5e-1 74
5 years 0.01 5.13 [3.45, 7.65] 8.3e-16 85
1 year - - - -

Age distribution of first events

01020304050607080050100150200250300350ageindividuals

Year distribution of first events

1970197519851990199520002005201020152021050100150200250300350400450500550600yearindividuals

Cumulative Incidence

Correlations

Index endpoint: R18_ABNORMAL_WEIGHT_LOSS – Abnormal weight loss
GWS hits: 0

Survival analyses between endpoints

Plot

before Abnormal weight loss
after Abnormal weight loss

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Abnormal weight loss